Sex Difference of Aortic Calcification

Sex differences in aortic valve calcification.

Aortic calcification.

Aortic calcification is a common finding in the elderly, and is usually in the aortic knuckle and descending thoracic aorta, often being associated with atheromatous fusiform dilatation and tortuosity of the aorta. Dense calcification in the ascending aorta is uncommon in atheromatous aortitis but is almost pathognomic of syphilitic aortitis with or without a saccular aneurysm. Calcification in...

Sex differences in aortic valve calcification measured by multidetector computed tomography in aortic stenosis.

BACKGROUND Aortic valve calcification (AVC) is the intrinsic mechanism of valvular obstruction leading to aortic stenosis (AS) and is measurable by multidetector computed tomography. The link between sex and AS is controversial and that with AVC is unknown. METHODS AND RESULTS We prospectively performed multidetector computed tomography in 665 patients with AS (aortic valve area, 1.05±0.35 cm...

Human aortic valve calcification.

To the Editor: Rajamannan et al1 addressed the problem of bone formation in calcified aortic valves, quoting the publication of actual bone formation by Mohler et al.2 Mohler et al had indicated that ossification in calcified aortic valves was relatively common, finding evidence of valve ossification in 36 of 323 patients. Of historical interest, I reported ossification in the left ventricular ...

Calcification of bicuspid aortic valves.

Over the past decade, our concept of the pathogenesis of calcific aortic valve disease has undergone a major transformation. We now recognise that calcific valve disease is the end stage of an active disease process and is not caused by “wear and tear” of the valve tissue. Immunohistochemical studies of trileaflet aortic valves with varying degrees of valve stenosis have demonstrated the presen...